Ramp-ing up allergies: Nramp1 (Slc11a1), macrophages and the hygiene hypothesis

Trends Immunol. 2004 Jul;25(7):342-7. doi: 10.1016/j.it.2004.04.010.

Authors

Joost J Smit¹, Gert Folkerts, Frans P Nijkamp

Affiliation

¹ Department of Pharmacology and Pathophysiology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80082, 3508 TB Utrecht, The Netherlands.

PMID: 15207500
DOI: 10.1016/j.it.2004.04.010

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Cation Transport Proteins / genetics
Cation Transport Proteins / immunology*
Cation Transport Proteins / physiology
Dinoprostone / immunology
Dinoprostone / physiology
Helminthiasis / immunology
Humans
Hygiene*
Hypersensitivity / etiology
Hypersensitivity / immunology*
Immunity, Innate / immunology
Interleukin-10 / immunology
Interleukin-10 / physiology
Macrophages / immunology*
Macrophages / metabolism
Macrophages / physiology
Models, Immunological
Mycobacterium Infections / immunology
Nitric Oxide / immunology
Nitric Oxide / physiology

Substances

Cation Transport Proteins
natural resistance-associated macrophage protein 1
Interleukin-10
Nitric Oxide
Dinoprostone