CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals

Nat Rev Immunol. 2004 Jul;4(7):529-40. doi: 10.1038/nri1392.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Basic Helix-Loop-Helix Transcription Factors
  • CD4-Positive T-Lymphocytes / cytology
  • CD4-Positive T-Lymphocytes / immunology
  • CD8-Positive T-Lymphocytes / cytology
  • CD8-Positive T-Lymphocytes / immunology
  • Cell Differentiation
  • Cell Lineage
  • Core Binding Factor Alpha 3 Subunit
  • DNA-Binding Proteins / physiology
  • Enhancer Elements, Genetic
  • GATA3 Transcription Factor
  • Gene Expression Regulation
  • Gene Silencing
  • Homeodomain Proteins / physiology
  • Humans
  • Mice
  • Mice, Transgenic
  • T-Lymphocyte Subsets / cytology*
  • T-Lymphocyte Subsets / immunology
  • Thymus Gland / cytology*
  • Thymus Gland / immunology
  • Trans-Activators / physiology
  • Transcription Factor HES-1
  • Transcription Factors / physiology

Substances

  • Basic Helix-Loop-Helix Transcription Factors
  • Core Binding Factor Alpha 3 Subunit
  • DNA-Binding Proteins
  • GATA3 Transcription Factor
  • GATA3 protein, human
  • Gata3 protein, mouse
  • Hes1 protein, mouse
  • Homeodomain Proteins
  • Runx3 protein, human
  • Runx3 protein, mouse
  • Trans-Activators
  • Transcription Factor HES-1
  • Transcription Factors
  • HES1 protein, human