Multivariate estimation of the relative dose potency

Stat Med. 2004 Jul 30;23(14):2187-93. doi: 10.1002/sim.1826.

Abstract

As a follow-up to a previous publication we illustrate how multivariate analysis of dose-response trials can be done, providing single number, relative dose potency, results for the comparison between two treatments, also when a number of variables are measured.

Publication types

  • Comparative Study

MeSH terms

  • Administration, Inhalation
  • Anti-Asthmatic Agents / administration & dosage
  • Asthma / drug therapy
  • Blood Glucose / metabolism
  • Cross-Over Studies
  • Dose-Response Relationship, Drug*
  • Drug Evaluation / methods*
  • Electrocardiography
  • Heart Rate / drug effects
  • Humans
  • Multivariate Analysis*
  • Potassium / blood
  • Randomized Controlled Trials as Topic / methods*
  • Respiratory Function Tests
  • Thiazoles / administration & dosage

Substances

  • Anti-Asthmatic Agents
  • Blood Glucose
  • Thiazoles
  • sibenadet
  • Potassium