Transplanted renal artery stenosis (TRAS) is one of the major causes of poor blood pressure control, progressive renal dysfunction and finally renal graft failure in uremic patients receiving renal allograft transplantation. Percutaneous transluminal balloon angioplasty (PTA) with stenting is an effective treatment for TRAS but has rarely had validation for the ostial lesions of TRAS. We reported 2 patients developing drug-refractory hypertension along with impaired renal function who received PTA plus stent deployment therapy for severe ostial stenosis of graft renal artery. Both of the patients had improved allograft function gradually, and satisfactory blood pressure control after 3 months follow-up. In conjugation with balloon angioplasty, stenting could provide a safe and effective revascularization strategy in conjunction with balloon angioplasty for ostial lesions of TRAS.