15NH4+ ion movement inside d(G4T4G4)2 G-quadruplex is accelerated in the presence of smaller Na+ ions

Primoz Sket; Martin Crnugelj; Wiktor Kozminski; Janez Plavec

doi:10.1039/b406815g

15NH4+ ion movement inside d(G4T4G4)2 G-quadruplex is accelerated in the presence of smaller Na+ ions

Org Biomol Chem. 2004 Jul 21;2(14):1970-3. doi: 10.1039/b406815g. Epub 2004 Jun 16.

Authors

Primoz Sket¹, Martin Crnugelj, Wiktor Kozminski, Janez Plavec

Affiliation

¹ NMR center, National Institute of Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia.

PMID: 15254621
DOI: 10.1039/b406815g

Abstract

2D NMR studies demonstrate that the residence lifetime of 15NH4+ ions within the bimolecular G-quadruplex adopted by d(G4T4G4) is reduced from 270 ms in the presence of ammonium ions alone to 36 ms in the presence of Na+ ions.