Limitation of diagnostic laparoscopy for patients with a periampullary carcinoma

Eur J Surg Oncol. 2004 Aug;30(6):658-62. doi: 10.1016/j.ejso.2004.03.019.

Abstract

Background: Diagnostic laparoscopy has been generally accepted in staging of patients with a periampullary malignancy. In our institution diagnostic laparoscopy was routinely used since 1992. However, in 1998 it was eliminated from the protocol since in a prospective study a yield of only 13% was found with a histologically proven accuracy of 60% for distant metastases. The effect of implementation of the new protocol on the occurrence of unnecessary laparotomies and the outcome after bypass surgery was assessed.

Methods: Between January 1999 and December 2001, 186 consecutive patients with a potentially resectable periampullary carcinoma after radiological staging without diagnostic laparoscopy underwent explorative laparotomy with the intention to perform a curative pancreatoduodenectomy. Incidence of unresectability and outcome of palliative surgery were assessed.

Results: Resection could not be performed in 65 patients who underwent laparotomy because of metastatic disease (29 patients) and loco-regional tumour ingrowth (34 patients). These patients underwent a bypass procedure with a median survival of 216 days.

Conclusion: At laparotomy distant metastases were detected in 16% of the patients. Considering the fact that the detection rate of diagnostic laparoscopy is lower than 100%, the use of staging laparotomy is too limited to justify it as a routine procedure.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Ampulla of Vater*
  • Clinical Protocols
  • Common Bile Duct Neoplasms / mortality
  • Common Bile Duct Neoplasms / pathology
  • Common Bile Duct Neoplasms / surgery*
  • Female
  • Humans
  • Laparoscopy / methods*
  • Laparoscopy / mortality
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Palliative Care / methods*
  • Pancreaticoduodenectomy / methods*
  • Pancreaticoduodenectomy / mortality
  • Survival Analysis
  • Treatment Outcome