A new indolinepeptide from Paecilomyces sp. J300

Arch Pharm Res. 2004 Jun;27(6):604-9. doi: 10.1007/BF02980157.

Abstract

A new indolinepeptide (3) was isolated, together with two known compounds, a cerebroside (1) and an alloxazine (2), from silkworm larvae infected with Paecilomyces sp. J300. On the basis of spectroscopic data, their structures were elucidated as (4E, 8E, 2S, 2'R, 3R)-N-2'-hydroxyhexadecanoyl-1-O-beta-D-glucopyranosyl-9-methyl-4, 8-sphingadienine (1), 7,8-dimethylalloxazine (2) and 3beta,5-dihydroxy-1-N-methyl-indoline-2beta-carbonyl amino-D-alanyl-erythro-beta-hydoxyisoleucinyl-glycine (3).

MeSH terms

  • Animals
  • Bombyx / microbiology
  • Indoles / chemistry*
  • Indoles / isolation & purification
  • Oligopeptides / chemistry*
  • Oligopeptides / isolation & purification*
  • Paecilomyces / chemistry*
  • Peptides / chemistry*
  • Peptides / isolation & purification

Substances

  • 3beta,5-dihydroxy-1-N-methyl-indoline-2beta-carbonyl amino-D-alanyl-erythro-beta-hydoxyisoleucinyl-glycine
  • Indoles
  • Oligopeptides
  • Peptides
  • indoline