Treatment of heart failure with spironolactone--trial and tribulations

N Engl J Med. 2004 Aug 5;351(6):526-8. doi: 10.1056/NEJMp048144.
No abstract available

Publication types

  • Comment

MeSH terms

  • Adrenergic beta-Antagonists / pharmacology
  • Adrenergic beta-Antagonists / therapeutic use
  • Aging / physiology
  • Aldosterone / biosynthesis
  • Drug Therapy, Combination
  • Glomerular Filtration Rate
  • Heart Failure / drug therapy*
  • Humans
  • Hyperkalemia / chemically induced*
  • Kidney / physiology
  • Mineralocorticoid Receptor Antagonists / administration & dosage
  • Mineralocorticoid Receptor Antagonists / adverse effects*
  • Spironolactone / administration & dosage
  • Spironolactone / adverse effects*

Substances

  • Adrenergic beta-Antagonists
  • Mineralocorticoid Receptor Antagonists
  • Spironolactone
  • Aldosterone