Shigella serotypes among hospitalized patients in urban Bangladesh and their antimicrobial resistance

Epidemiol Infect. 2004 Aug;132(4):773-7. doi: 10.1017/s0950268804002134.

Abstract

We studied the isolation of Shigella spp., and their antimicrobial resistance. S. flexneri (54 %) was most frequently isolated, followed by S. dysenteriae (20 %), S. boydii (16 %) and S. sonnei (10 %). Among S. flexneri (n = 122), 29 (24 %) were 2a, and 23 (19 %) were 2b. None of the Shigella strains were resistant to mecillinam or ciprofloxacin. Resistance to nalidixic acid was most frequent among S. dysenteriae type 1 (100%) followed by S. flexneri 2a (69%), and S. flexneri 2b (52 %). Systematic monitoring is needed to identify most prevalent serotypes, and to detect changes in the prevalence and antimicrobial resistance pattern.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bangladesh / epidemiology
  • Cross Infection / epidemiology
  • Cross Infection / etiology
  • Cross Infection / microbiology
  • Drug Resistance, Bacterial*
  • Dysentery, Bacillary / epidemiology*
  • Dysentery, Bacillary / etiology
  • Dysentery, Bacillary / microbiology*
  • Hospitalization
  • Humans
  • Microbial Sensitivity Tests
  • Nalidixic Acid / pharmacology
  • Prevalence
  • Shigella / classification*
  • Shigella / drug effects*
  • Shigella / isolation & purification
  • Urban Health

Substances

  • Anti-Bacterial Agents
  • Nalidixic Acid