Objective: To observe the long-term outcomes following coronary stenting in diabetic patients with coronary artery disease.
Methods: This cohort study comprised 808 consecutive patients with coronary artery disease who underwent elective coronary stenting, including 174 diabetic patients and 634 non-diabetic patients. The long-term follow-up outcomes were compared.
Results: Procedural success rate was similar (96.0% vs 96.1%). Follow-up rate was 95.3%. Mean follow-up duration was (19 +/- 7.8) months (ranged from 6 to 42 months). Compared with non-diabetic patients, diabetic patients had less improvement of cardiac function (52.2% vs 61.0%), more re-admission (42.7% vs 32.5%), and higher occurrence rates of major adverse cardiac events (30.6% vs 22.2%), angiographic restenosis rate (19.1% vs 12.5%) and mortality (10.2% vs 4.6%). Logistic regression analysis indicated that diabetes mellitus was an independent predicator of death (odd ratio 2.20, 95% CI 1.12 approximately 4.33, P = 0.022) and restenosis (odd ratio 1.66, 95% CI 1.04 approximately 2.67, P = 0.035).
Conclusion: Diabetic patients undergoing elective coronary stenting have acceptable long-term outcomes, but diabetes mellitus is still independently associated with worse late prognosis.