Angiolymphoid hyperplasia with eosinophilia of the nail bed and bone: successful treatment with radiation therapy

J Eur Acad Dermatol Venereol. 2004 Sep;18(5):584-5. doi: 10.1111/j.1468-3083.2004.00976.x.

Abstract

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare entity characterized by the presence of one or several papules or nodules in the skin. Histopathology of ALHE shows a marked proliferation of blood vessels with distinctive large endothelial cells and variable inflammatory infiltrates with eosinophils. We report a 32-year-old Caucasian woman with multiple nodules involving the skin, subcutaneous tissue and bone of the distal phalanx of the fingers that were treated successfully with orthovoltage radiation therapy (40 Gy/20 fractions) and without any side-effects after 9 years of follow-up.

MeSH terms

  • Adult
  • Angiolymphoid Hyperplasia with Eosinophilia / diagnosis*
  • Angiolymphoid Hyperplasia with Eosinophilia / pathology
  • Angiolymphoid Hyperplasia with Eosinophilia / radiotherapy
  • Bone Diseases / diagnosis*
  • Bone Diseases / pathology
  • Bone Diseases / radiotherapy
  • Diagnosis, Differential
  • Female
  • Forearm
  • Hand
  • Humans
  • Nail Diseases / diagnosis*
  • Nail Diseases / pathology
  • Nail Diseases / radiotherapy