Selective oxidation of a single primary alcohol function in oligopyridine frameworks

Org Lett. 2004 Aug 19;6(17):2865-8. doi: 10.1021/ol0491843.

Abstract

A variety of mono-oxidized pyridine, bipyridine, terpyridine, and pyridine/pyridazine are readily prepared under mild conditions using Pyrolusite MnO2. This phase has been characterized by means of X-ray powder diffraction and scanning electron microscopy. The oxidative activity is in keeping with the nature, morphology, and surface area of the MnO2 reagent.