High incidence of type 2 diabetes in peroxisome proliferator-activated receptor gamma2 Pro12Ala carriers exposed to a high chronic intake of trans fatty acids and saturated fatty acids

Diabetes Care. 2004 Sep;27(9):2251-2. doi: 10.2337/diacare.27.9.2251.
No abstract available

MeSH terms

  • Adult
  • Alanine
  • Amino Acid Substitution*
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Diabetes Mellitus, Type 2 / genetics*
  • Dietary Fats*
  • Energy Intake
  • Female
  • Genetic Carrier Screening
  • Humans
  • Male
  • Middle Aged
  • PPAR gamma / genetics*
  • Pilot Projects
  • Point Mutation*
  • Polymorphism, Single Nucleotide
  • Proline
  • Risk Factors
  • Trans Fatty Acids*
  • Uruguay

Substances

  • Dietary Fats
  • PPAR gamma
  • Trans Fatty Acids
  • Proline
  • Alanine