Aerosolized iloprost as a bridge to lung transplantation in a patient with cystic fibrosis and pulmonary hypertension

Pierre Tissières; Laurent Nicod; Constance Barazzone-Argiroffo; Peter C Rimensberger; Maurice Beghetti

doi:10.1016/j.athoracsur.2003.12.096

Aerosolized iloprost as a bridge to lung transplantation in a patient with cystic fibrosis and pulmonary hypertension

Ann Thorac Surg. 2004 Sep;78(3):e48-50. doi: 10.1016/j.athoracsur.2003.12.096.

Authors

Pierre Tissières¹, Laurent Nicod, Constance Barazzone-Argiroffo, Peter C Rimensberger, Maurice Beghetti

Affiliation

¹ Unit of Pediatric Cardiology, University Children's Hospital, Geneva, Switzerland.

PMID: 15337084
DOI: 10.1016/j.athoracsur.2003.12.096

Abstract

We describe a patient with cystic fibrosis, end-stage lung disease, and secondary pulmonary hypertension in whom aerosolized iloprost was effective in lowering pulmonary artery pressure and improving functional status, thus proving successful as a bridge to lung transplantation. Inhaled iloprost may be an efficient and selective approach to treat pulmonary hypertension related to end-stage obstructive pulmonary disease.

Publication types

Case Reports

MeSH terms

Administration, Inhalation
Adult
Cystic Fibrosis / complications*
Female
Humans
Hypertension, Pulmonary / complications*
Hypertension, Pulmonary / drug therapy
Iloprost / administration & dosage*
Lung Transplantation / methods*
Nitric Oxide / administration & dosage
Premedication*
Respiratory Insufficiency / etiology
Respiratory Insufficiency / surgery*
Vascular Resistance / drug effects
Vasodilator Agents / administration & dosage*

Substances

Vasodilator Agents
Nitric Oxide
Iloprost