Naps and circadian rhythms in postmenopausal women

J Gerontol A Biol Sci Med Sci. 2004 Aug;59(8):844-8. doi: 10.1093/gerona/59.8.m844.

Abstract

Background: Napping patterns and relationships among naps, circadian rhythms, and nocturnal sleep were evaluated in postmenopausal women. Naps and nocturnal sleep were compared between depressed women and healthy volunteers.

Methods: The study included 436 postmenopausal women between the ages of 50 and 81 years. Psychiatric interviews were conducted using the Structured Clinical Interview for DSM-IV Axis I Disorders. Each participant wore a wrist-activity monitor and kept a daily sleep log at home for 1 week. The major urinary melatonin metabolite (6-sulfatoxymelatonin [aMT6s]) was measured for two 24-hour periods at home.

Results: There was no significant difference in naps and nocturnal sleep patterns between depressed participants (n = 30) and those with no history of mental disorder (n = 222). Three peaks occurred in the timing of napping: approximately 1 hour before bedtime, 8 to 9 hours after wake-up time, and 2 hours after waking, in descending order of magnitude. Significant inverse correlations were observed between evening nap duration and both wake-up time and aMT6s acrophase. The onset time of aMT6s excretion was advanced by 32 minutes in evening nappers.

Conclusions: Evening napping, a characteristic of these postmenopausal women, may be related to an advance of circadian rhythms in this age group. Relationships between evening napping and earlier wake-up time may be a common manifestation of advanced circadian rhythms or may be a homeostatic effect.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Circadian Rhythm / physiology*
  • Depression / physiopathology
  • Female
  • Humans
  • Interview, Psychological
  • Melatonin / analogs & derivatives*
  • Melatonin / urine
  • Middle Aged
  • Postmenopause / physiology*
  • Sleep / physiology*

Substances

  • 6-sulfatoxymelatonin
  • Melatonin