The evolution of adjuvant and neoadjuvant chemotherapy and radiation for advanced pancreatic cancer: from 5-fluorouracil to GTX

Surg Oncol Clin N Am. 2004 Oct;13(4):711-35, x. doi: 10.1016/j.soc.2004.06.005.

Abstract

This article reviews the relevant literature and reports on The Columbia University Medical Center experience with chemoradiation for pancreatic cancer.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Chemotherapy, Adjuvant
  • Clinical Trials, Phase I as Topic
  • Combined Modality Therapy
  • Deoxycytidine / administration & dosage
  • Deoxycytidine / analogs & derivatives*
  • Female
  • Fluorouracil / administration & dosage
  • Gemcitabine
  • Humans
  • Male
  • Maximum Tolerated Dose
  • Middle Aged
  • Neoadjuvant Therapy*
  • Neoplasm Staging
  • Pancreatectomy / methods
  • Pancreatic Neoplasms / mortality
  • Pancreatic Neoplasms / pathology*
  • Pancreatic Neoplasms / therapy*
  • Postoperative Care
  • Preoperative Care
  • Prognosis
  • Radiotherapy Dosage
  • Radiotherapy, Adjuvant
  • Survival Analysis
  • Treatment Outcome

Substances

  • Deoxycytidine
  • Fluorouracil
  • Gemcitabine