Isolation, crystal and solution structure determination, and biosynthesis of tubulysins--powerful inhibitors of tubulin polymerization from myxobacteria

Angew Chem Int Ed Engl. 2004 Sep 20;43(37):4888-92. doi: 10.1002/anie.200460147.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biopolymers / antagonists & inhibitors*
  • Biopolymers / metabolism*
  • Crystallization
  • Crystallography, X-Ray
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Myxococcales / chemistry*
  • Oligopeptides / biosynthesis*
  • Oligopeptides / chemistry*
  • Oligopeptides / isolation & purification
  • Oligopeptides / pharmacology
  • Solutions
  • Tubulin / metabolism*
  • Tubulin Modulators*

Substances

  • Biopolymers
  • Oligopeptides
  • Solutions
  • Tubulin
  • Tubulin Modulators
  • tubulysin D