3D-model of the ion channel of NMDA receptor: qualitative and quantitative modeling of the blocker binding

Dokl Biochem Biophys. 2004 May-Jun:396:181-6. doi: 10.1023/b:dobi.0000033524.51696.37.

Authors

I G Tikhonova¹, I I Baskin, V A Palyulin, N S Zefirov

Affiliation

¹ Moscow State University, Vorob'evy gory, Moscow, 119899 Russia.

PMID: 15378922
DOI: 10.1023/b:dobi.0000033524.51696.37

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Computer Simulation
Excitatory Amino Acid Antagonists / chemistry*
Excitatory Amino Acid Antagonists / metabolism*
Excitatory Amino Acid Antagonists / pharmacology
Ion Channels / antagonists & inhibitors*
Ion Channels / chemistry*
Ion Channels / metabolism
Models, Molecular*
Molecular Sequence Data
Phencyclidine / metabolism
Protein Binding
Quantitative Structure-Activity Relationship
Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors*
Receptors, N-Methyl-D-Aspartate / chemistry*
Receptors, N-Methyl-D-Aspartate / metabolism

Substances

Excitatory Amino Acid Antagonists
Ion Channels
Receptors, N-Methyl-D-Aspartate
Phencyclidine