Clinical situations demanding weaning from long-term ventricular assist devices

Eur J Cardiothorac Surg. 2004 Oct;26(4):730-5. doi: 10.1016/j.ejcts.2004.07.020.

Abstract

Objective: Ventricular assist devices are increasingly used to treat patients with acute or chronic end-stage heart failure. We report on circumstances, exemplified on four cases, where a surprisingly favorable clinical course of the patients ultimately demanded early explantation of the device, which was not anticipated prior to its implantation.

Methods: The four patients were provided with implantable (Micromed BeBakey trade mark, Incor trade mark ) and external pneumatically driven (Thoratec trade mark, Excor trade mark ) devices under emergency conditions and were listed for heart transplantation.

Results: All four patients had an unexpected recovery of myocardial pump function. After careful diagnostic evaluation, all device components were completely removed without extracorporeal circulation. No stepwise weaning protocol was employed.

Conclusions: Weaning patients from ventricular assist devices after recovery of myocardial pump function can become necessary. Diagnostic evaluation and the implementation of a weaning protocol is still a matter of debate, while complete surgical removal of all device components without extracorporeal circulation is possible with a low risk.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Cardiomyopathy, Dilated / therapy
  • Cerebral Hemorrhage / etiology
  • Device Removal / methods*
  • Female
  • Graft Rejection
  • Heart Failure / therapy*
  • Heart Transplantation
  • Heart-Assist Devices* / adverse effects
  • Humans
  • Male
  • Myocardial Infarction / therapy