Six month radiological and physiological outcomes in severe acute respiratory syndrome (SARS) survivors

Thorax. 2004 Oct;59(10):889-91. doi: 10.1136/thx.2004.023762.

Abstract

Background: The long term physiological and radiological outcomes of SARS survivors and their possible determinants are uncertain.

Methods: SARS survivors in a follow up clinic in a regional hospital underwent high resolution computed tomography (HRCT) of the thorax and lung function tests 6 months after admission to hospital. The associations between the clinical and demographic data of the patients and the physiological and radiological outcomes were examined.

Results: Fifty seven patients took part in the study. Lung function abnormalities were detected in 43 patients (75.4%), with restrictive defects (n = 16) being most common (28.1%). Radiological abnormalities of any degree were detected in 43 patients (75.4%). Only the use of pulse corticosteroids was associated with the presence of CT abnormalities (p = 0.043, OR 6.65, 95% CI 1.06 to 41.73).

Conclusions: Physiological and radiological abnormalities are still present in a considerable proportion of SARS survivors at 6 months.

MeSH terms

  • Adult
  • Female
  • Forced Expiratory Volume / physiology
  • Humans
  • Male
  • Prognosis
  • Severe Acute Respiratory Syndrome / diagnostic imaging*
  • Severe Acute Respiratory Syndrome / physiopathology
  • Tomography, X-Ray Computed / methods
  • Total Lung Capacity / physiology