According to health politicians at present, the modernisation of the health care system is a continuous task of the health policy of governments. The core of this modernisation: to have information about the needs of the population and the patients, to ensure immaterial and material conditions of health care, to organise and direct the process of health care in the interests of the favourable results of the outcome of care activities. The fundamental conditions of the modernisation to update the health information systems are harmonised on an international level. The main goal of the bilateral program is: to develop and introduce health informatics telemedicine systems for transmission and integration of information systems and health data between structures in Hungary and Italy. The program contemplates doing problem-oriented electronic patients record structures with a flexible, interactive and high operation-speed knowledge basis network for health institutes of both countries.