Performance of the Binax NOW Streptococcus pneumoniae urinary antigen assay for diagnosis of pneumonia in children with underlying pulmonary diseases in the absence of acute pneumococcal infection

David Navarro; Leonor García-Maset; Concepción Gimeno; Amparo Escribano; Juan García-de-Lomas; Spanish Pneumococcal Infection Study Network

doi:10.1128/JCM.42.10.4853-4855.2004

Performance of the Binax NOW Streptococcus pneumoniae urinary antigen assay for diagnosis of pneumonia in children with underlying pulmonary diseases in the absence of acute pneumococcal infection

J Clin Microbiol. 2004 Oct;42(10):4853-5. doi: 10.1128/JCM.42.10.4853-4855.2004.

Authors

David Navarro¹, Leonor García-Maset, Concepción Gimeno, Amparo Escribano, Juan García-de-Lomas; Spanish Pneumococcal Infection Study Network

Affiliation

¹ Department of Microbiology, University Clinical Hospital, Valencia, Spain.

Abstract

The performance of the Binax NOW immunochromatographic test for detecting Streptococcus pneumoniae antigen in urine specimens from 103 children presenting underlying pulmonary diseases with no recent pneumococcal infection was assessed. Our data indicate that this assay is unlikely to be useful for discriminating between children with and without pneumococcal pneumonia.

Publication types

Evaluation Study

MeSH terms

Adolescent
Antigens, Bacterial / urine*
Child
Child, Preschool
Chromatography
Female
Humans
Immunoassay / methods
Infant
Lung Diseases / complications*
Male
Pneumococcal Infections / microbiology
Pneumonia, Pneumococcal / diagnosis*
Pneumonia, Pneumococcal / microbiology
Reagent Kits, Diagnostic*
Sensitivity and Specificity
Streptococcus pneumoniae / isolation & purification*

Substances

Antigens, Bacterial
Reagent Kits, Diagnostic