Catching proteases in action with microarrays

Howard C Hang; Hidde Ploegh

doi:10.1016/j.chembiol.2004.09.005

Catching proteases in action with microarrays

Chem Biol. 2004 Oct;11(10):1328-30. doi: 10.1016/j.chembiol.2004.09.005.

Authors

Howard C Hang¹, Hidde Ploegh

Affiliation

¹ Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.

PMID: 15489158
DOI: 10.1016/j.chembiol.2004.09.005

Abstract

Proteases regulate many essential functions in biology, yet their precise roles are only beginning to be unraveled. In this issue, two related papers describe a novel method to dissect specific protease activities from complex mixtures.

Publication types

Comment
Review

MeSH terms

Animals
Humans
Peptide Hydrolases / genetics
Peptide Hydrolases / metabolism
Peptide Hydrolases / physiology*
Protein Array Analysis / methods*

Substances

Peptide Hydrolases