Osteopenia and osteoporosis in HIV+ patients, untreated or receiving HAART

Biomed Pharmacother. 2004 Nov;58(9):505-8. doi: 10.1016/j.biopha.2004.08.019.

Abstract

In the last few years there are increasing evidences suggesting that osteopenia and osteoporosis are frequent among HIV positive patients. It is still not clear if the bone demineralization is a direct consequence of viral infection or of the antiretroviral drugs. Studies to date therefore give conflicting results. We performed a study to evaluate the prevalence of osteopenia and osteoporosis in HIV positive patients, either untreated or receiving antiretroviral therapy, to asses the frequency of these conditions and the role of antiretroviral drugs.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Adult
  • Analysis of Variance
  • Antiretroviral Therapy, Highly Active / adverse effects*
  • Bone Density / drug effects
  • Bone Density / physiology
  • Bone Diseases, Metabolic / chemically induced
  • Bone Diseases, Metabolic / diagnostic imaging*
  • Bone Diseases, Metabolic / epidemiology
  • Chi-Square Distribution
  • Female
  • HIV Infections / diagnostic imaging*
  • HIV Infections / drug therapy*
  • HIV Infections / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Osteoporosis / chemically induced
  • Osteoporosis / diagnostic imaging
  • Osteoporosis / epidemiology
  • Ultrasonography