Continuous measurement of cerebral blood volume and oxygenation during rewarming of neonates

Acta Paediatr. 2004 Nov;93(11):1540-2. doi: 10.1080/08035250410033934.

Abstract

Aim: To investigate the effect of rewarming in preterm infants presenting with hypothermia at admission.

Methods: The tissue oxygenation index (TOI), changes in cerebral blood volume (DeltaCBV) and changes in intravascular oxygenation (DeltaHbD) were measured in eight preterm infants, presenting with a temperature less than 35 degrees C at admission.

Results: A significant increase in HbD and TOI was seen in four patients (group A), while a significant increase in CBV and a decrease in HbD was seen in four other patients (group B). Retrospective analysis showed that group A had important signs of peripartal asphyxia.

Conclusion: While infants with peripartal asphyxia showed an important increase in oxygenation during rewarming, no significant changes were seen in the non-asphyxiated infants.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asphyxia Neonatorum / physiopathology
  • Cerebrovascular Circulation
  • Humans
  • Hypothermia / physiopathology
  • Hypothermia / therapy*
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases / physiopathology
  • Infant, Premature, Diseases / therapy*
  • Oxygen Consumption
  • Rewarming*
  • Spectroscopy, Near-Infrared