Abstract
Thirty-three patients with 35 bone lesions suspicious for osteosarcoma underwent image-guided biopsy. Of those 35 biopsies, 12 were performed with use of fluoroscopy or computed tomography (CT) guidance to target the osseous abnormality. Diagnostic magnetic resonance imaging revealed a soft tissue component in 23 cases; in these cases, biopsies were performed with use of ultrasonography (US) to target the soft tissue component of the tumor. Of the 35 tumors in which biopsy was performed, 33 (94%) were definitively diagnosed as osteosarcoma by image-guided biopsy. All 23 US-guided biopsies resulted in definitive diagnosis. Two of the 12 fluoroscopy- or CT-guided biopsies (17%) were inconclusive.
MeSH terms
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Adolescent
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Adult
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Antibiotics, Antineoplastic / therapeutic use
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Antineoplastic Agents / therapeutic use
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Biopsy, Needle / methods
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Bone Neoplasms / diagnosis*
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Bone Neoplasms / drug therapy
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Bone Neoplasms / surgery
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Chemotherapy, Adjuvant / methods
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Child
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Cisplatin / therapeutic use
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Diagnosis, Differential
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Doxorubicin / therapeutic use
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Female
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Fluoroscopy / methods
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Humans
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Humerus / diagnostic imaging
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Humerus / pathology
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Leg Bones / diagnostic imaging
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Leg Bones / pathology
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Male
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Osteosarcoma / diagnosis*
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Osteosarcoma / drug therapy
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Osteosarcoma / surgery
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Radius / diagnostic imaging
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Radius / pathology
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Retrospective Studies
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Tomography, X-Ray Computed / methods
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Ultrasonography / methods*
Substances
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Antibiotics, Antineoplastic
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Antineoplastic Agents
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Doxorubicin
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Cisplatin