Abstract
Analysis of short sequence repeats of Mycobacterium avium subsp. paratuberculosis isolated from Crohn's disease patients identified two alleles, both of which clustered with strains derived from animals with Johne's disease. Identification of a limited number of genotypes among human strains implies the existence of human disease-associated genotypes and strain sharing with animals.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Alleles
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Animals
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Cattle
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Cattle Diseases / microbiology
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Crohn Disease / microbiology*
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DNA, Bacterial / analysis
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Goat Diseases / microbiology
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Goats
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Humans
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Microsatellite Repeats / genetics*
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Mycobacterium avium subsp. paratuberculosis / classification*
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Mycobacterium avium subsp. paratuberculosis / genetics
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Mycobacterium avium subsp. paratuberculosis / isolation & purification
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Paratuberculosis / microbiology*
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Polymorphism, Genetic*
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Sheep
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Sheep Diseases / microbiology