Quantitative phase imaging using actively stabilized phase-shifting low-coherence interferometry

Opt Lett. 2004 Oct 15;29(20):2399-401. doi: 10.1364/ol.29.002399.

Abstract

We describe a quantitative phase-imaging interferometer in which phase shifting and noise cancellation are performed by an active feedback loop using a reference laser. Depth gating via low-coherence light allows phase measurement from weakly reflecting biological samples. We demonstrate phase images from a test structure and living cells.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Equipment Design
  • Equipment Failure Analysis
  • HeLa Cells / pathology*
  • Humans
  • Image Enhancement / instrumentation*
  • Image Enhancement / methods
  • Interferometry / instrumentation*
  • Interferometry / methods
  • Phantoms, Imaging
  • Tomography, Optical Coherence / instrumentation*
  • Tomography, Optical Coherence / methods