Molecules that cause or prevent Parkinson's disease

PLoS Biol. 2004 Nov;2(11):e401. doi: 10.1371/journal.pbio.0020401. Epub 2004 Nov 16.

Abstract

An overview of the molecules and associated cell biology underlying neuron death in Parkinson's Disease

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / pathology
  • Disease Models, Animal
  • Evolution, Molecular
  • Humans
  • Intracellular Signaling Peptides and Proteins
  • Models, Biological
  • Mutation*
  • Neurons / metabolism*
  • Oncogene Proteins / genetics
  • Parkinson Disease / etiology
  • Parkinson Disease / genetics*
  • Parkinson Disease / prevention & control*
  • Protein Deglycase DJ-1
  • Protein Kinases / genetics
  • Synucleins / genetics
  • Ubiquitin-Protein Ligases / genetics

Substances

  • Intracellular Signaling Peptides and Proteins
  • Oncogene Proteins
  • Synucleins
  • Ubiquitin-Protein Ligases
  • parkin protein
  • Protein Kinases
  • PTEN-induced putative kinase
  • PARK7 protein, human
  • Protein Deglycase DJ-1