Abstract
Among 563 strains of Haemophilus influenzae from young children in Hong Kong, 5 (0.9%) had decreased susceptibility to quinolones. The five strains had a Ser-84-Lys or Asp-88-Asn substitution in GyrA. Pulsed-field gel electrophoresis showed that the isolates are genetically diverse.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Carrier State
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Child
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Child, Preschool
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Drug Resistance, Bacterial*
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Haemophilus influenzae / drug effects*
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Hong Kong
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Humans
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Infant
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Levofloxacin*
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Nalidixic Acid / pharmacology
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Nasopharynx / microbiology
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Ofloxacin / pharmacology*
Substances
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Anti-Bacterial Agents
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Nalidixic Acid
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Levofloxacin
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Ofloxacin