An overview of the role of insulin in the treatment of hyperglycemia during acute myocardial ischemia

Can J Cardiol. 2004 Nov;20(13):1361-5.

Abstract

Hyperglycemia on admission to the coronary care unit is associated with poor outcome. It has now been reasonably well established that intravenous insulin infusion during acute myocardial infarction has a protective role and reduces mortality. The present article reviews the current understanding of the cardioprotective effect of insulin and the recent advances in this area.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Coronary Care Units
  • Critical Care / methods
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Female
  • Humans
  • Hyperglycemia / drug therapy*
  • Hyperglycemia / etiology
  • Hyperglycemia / mortality
  • Infusions, Intravenous
  • Insulin / therapeutic use*
  • Male
  • Myocardial Infarction / complications*
  • Myocardial Infarction / diagnosis
  • Myocardial Infarction / mortality
  • Myocardial Ischemia / physiopathology
  • Prognosis
  • Risk Assessment
  • Severity of Illness Index
  • Survival Analysis
  • Treatment Outcome

Substances

  • Insulin