Using modified antigenic sequences to develop cancer vaccines: are we losing the focus?

PLoS Med. 2004 Nov;1(2):e26. doi: 10.1371/journal.pmed.0010026. Epub 2004 Nov 30.

Abstract

Are short synthetic peptides the key to developing cancer vaccines? And what are the obstacles in the way?

MeSH terms

  • Antigens, Neoplasm / immunology*
  • Cancer Vaccines / immunology*
  • Humans
  • Major Histocompatibility Complex / immunology
  • T-Lymphocytes, Cytotoxic

Substances

  • Antigens, Neoplasm
  • Cancer Vaccines