Clinical evaluation of the gen-probe amplified mycobacterium tuberculosis direct test for rapid diagnosis of tuberculosis lymphadenitis

A Kerleguer; M Fabre; J J Bernatas; P Gerome; E Nicand; V Herve; J L Koeck

doi:10.1128/JCM.42.12.5921-5922.2004

Clinical evaluation of the gen-probe amplified mycobacterium tuberculosis direct test for rapid diagnosis of tuberculosis lymphadenitis

J Clin Microbiol. 2004 Dec;42(12):5921-2. doi: 10.1128/JCM.42.12.5921-5922.2004.

Authors

A Kerleguer¹, M Fabre, J J Bernatas, P Gerome, E Nicand, V Herve, J L Koeck

Affiliation

¹ Laboratoire de Biologie Clinique, HIA Val-de-Grāce, Paris, France.

Abstract

This prospective study evaluated the performance of the Amplified Mycobacterium Tuberculosis Direct Test (MTD) for the diagnosis of lymph node tuberculosis in Djibouti, Republic of Djibouti. Of 197 specimens sampled from 153 patients, 123 were from 95 tuberculous patients. The sensitivity and specificity of MTD were 93 and 100%, respectively. The sensitivity of culture was 89%.

Publication types

Evaluation Study

MeSH terms

Culture Media
DNA Probes*
Humans
Mycobacterium tuberculosis / genetics
Mycobacterium tuberculosis / isolation & purification*
Nucleic Acid Amplification Techniques / methods*
Prospective Studies
RNA, Bacterial / analysis
Sensitivity and Specificity
Time Factors
Tuberculosis, Lymph Node / diagnosis*
Tuberculosis, Lymph Node / microbiology

Substances

Culture Media
DNA Probes
RNA, Bacterial