[Usefulness of conscious sedation with midazoram during transesophageal echocardiographic examination]

J Cardiol. 2004 Nov;44(5):195-200.
[Article in Japanese]

Abstract

Objectives: Although transesophageal echocardiography is useful to identify various cardiovascular diseases, the semi-invasive nature of the examination hampers its routine application. We investigated whether conscious sedation using a low dose of intravenous midazoram was safe and useful during the examination.

Methods: We asked 55 consecutive patients undergoing transesophageal echocardiography (44 with midazoram, mean age 59 +/- 16 years, and 11 without midazoram, mean age 62 +/- 8 years) and the examiners about the effects of midazoram using a questionnaire.

Results: The mean dose of midazoram was 2.2 mg (range 1-3.5 mg). All examinations were done without any adverse events. Eighty-two percent of the patients with midazoram considered the examination under conscious sedation tolerable, whereas 91% without midazoram felt it untolerable. Most examiners felt manipulation of the echo probe was easier in patients with midazoram than in those without (69% vs 27%).

Conclusions: Conscious sedation with a low dose of intravenous midazoram facilitated and increased patient tolerance during transesophageal echocardiographic examination.

MeSH terms

  • Aged
  • Anesthetics, Intravenous*
  • Arrhythmias, Cardiac / diagnostic imaging
  • Conscious Sedation*
  • Dose-Response Relationship, Drug
  • Echocardiography, Transesophageal* / standards
  • Female
  • Heart Valve Diseases / diagnostic imaging*
  • Humans
  • Male
  • Midazolam*
  • Middle Aged
  • Surveys and Questionnaires

Substances

  • Anesthetics, Intravenous
  • Midazolam