Right-handed helical structure of expanded oligo(L-leucine) containing [Ru(terpyridine)2]2+ moieties

J Am Chem Soc. 2004 Dec 15;126(49):15972-3. doi: 10.1021/ja044310j.

Abstract

Expanded oligo(l-leucine)s, containing an alternate arrangement of a bis(terpyridine)ruthenium(II) moiety and a l-leucine residue, were synthesized and characterized by 1H NMR, UV, CD, and electrochemical properties. The intensity of CD spectra per ruthenium unit increased with the elongation of the peptide chain. 1H NMR analysis of a tetramer indicated the right-handed helical structure in acetonitrile.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Circular Dichroism
  • Models, Molecular
  • Oligopeptides / chemistry
  • Organometallic Compounds / chemistry*
  • Peptides / chemistry*
  • Protein Structure, Secondary
  • Pyridines / chemistry*
  • Ruthenium / chemistry*
  • Spectrophotometry, Ultraviolet

Substances

  • Oligopeptides
  • Organometallic Compounds
  • Peptides
  • Pyridines
  • polyleucine
  • Ruthenium