Usefulness of N-terminal-pro-brain natriuretic peptide levels in predicting survival in heart transplant recipients

Am J Cardiol. 2004 Dec 15;94(12):1585-7. doi: 10.1016/j.amjcard.2004.08.049.

Abstract

We evaluated the prognostic value of plasma N-terminal-pro-brain natriuretic peptide (NT-pro-BNP) in 71 transplanted heart recipients during a 38 +/- 2 month follow-up. The negative predictive value of NT-pro-BNP levels </=800 pg/ml to predict death was 97% (95% confidence interval 92 to 100). Thus, NT-pro-BNP levels </=800 pg/ml predict a middle-term good survival in transplanted heart recipients.

MeSH terms

  • Biomarkers / blood*
  • Female
  • Follow-Up Studies
  • Heart Failure / surgery
  • Heart Transplantation / mortality*
  • Humans
  • Male
  • Middle Aged
  • Natriuretic Peptide, Brain
  • Nerve Tissue Proteins / blood*
  • Peptide Fragments / blood*
  • Prognosis
  • Survival Rate

Substances

  • Biomarkers
  • Nerve Tissue Proteins
  • Peptide Fragments
  • pro-brain natriuretic peptide (1-76)
  • Natriuretic Peptide, Brain