Mechanisms of resistance development against trastuzumab (Herceptin) in an in vivo breast cancer model

Int J Clin Pharmacol Ther. 2004 Nov;42(11):642-3. doi: 10.5414/cpp42642.
No abstract available

MeSH terms

  • Animals
  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents / therapeutic use*
  • Drug Resistance, Neoplasm
  • Erlotinib Hydrochloride
  • Female
  • Mice
  • Mice, Inbred BALB C
  • Protein Kinase Inhibitors / therapeutic use
  • Quinazolines / therapeutic use
  • Rats
  • Receptor, ErbB-2 / antagonists & inhibitors*
  • Trastuzumab

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents
  • Protein Kinase Inhibitors
  • Quinazolines
  • Erlotinib Hydrochloride
  • Receptor, ErbB-2
  • Trastuzumab