Abstract
Bovine herpesvirus type 5 (BHV-5) is the causative agent of bovine herpetic encephalitis, a major concern for cattle farming in Brazil and Argentina. We recently developed a differential, gE-negative vaccine (265 gE-), based on a Brazilian BHV-1 strain. The present study was carried out to examine whether such a vaccine would confer protection to BHV-5 infections. It was concluded that the recombinant BHV-1 vaccine tested here is not capable of conferring full protection to BHV-5 challenge.
MeSH terms
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Animals
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Antibody Formation
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Cattle
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Cattle Diseases / immunology
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Cattle Diseases / prevention & control*
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Encephalitis, Viral / immunology
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Encephalitis, Viral / prevention & control*
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Encephalitis, Viral / veterinary*
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Herpesviridae Infections / immunology
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Herpesviridae Infections / prevention & control*
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Herpesviridae Infections / veterinary*
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Herpesvirus 1, Bovine / immunology*
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Herpesvirus 5, Bovine / immunology*
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Herpesvirus 5, Bovine / pathogenicity*
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Meningoencephalitis / immunology
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Meningoencephalitis / prevention & control*
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Meningoencephalitis / veterinary*
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Vaccination / veterinary
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Viral Vaccines