Abstract
This review focuses on caffeine's effects on the central modulation of muscle activation in humans. The drug's effects on voluntary muscle activation, the Hoffman reflex, motor-evoked potentials, self-sustained firing, pain, and sensation are discussed, and the possibility that caffeine maybe useful in the study of central fatigue is explored.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Caffeine / pharmacology*
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Central Nervous System Stimulants / pharmacology*
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Evoked Potentials, Motor / drug effects
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Exercise / physiology*
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Fatigue / metabolism*
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Humans
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Motor Cortex / drug effects
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Muscle Contraction / drug effects*
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Muscle, Skeletal / drug effects*
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Muscle, Skeletal / innervation
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Reaction Time
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Receptors, Serotonin / drug effects
Substances
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Central Nervous System Stimulants
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Receptors, Serotonin
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Caffeine