The variability in clinical appearance of vulvar tumors suggests that biopsy confirmation should be obtained for all lesions for which there is the least doubt in the diagnosis. Pigmented vulvar lesions are present in 10% to 12% of white women and the labia minora are the most common site for vulvar melanomas and atypical melanocytic nevi. Therefore, to perform a correct reconstruction, the surgeon must absolutely have a good understanding of the anatomy of the labia minora, as well as of the surgical options available, one of which is the wedge resection in the vulvar region. A classical clinical case will be used here to highlight the usefulness of wedge resection, a simple surgical technique that is applicable to the labia minora of the vulva in addition to its standard anatomic sites (auricle, lip, and eyelid).