Abstract
Allelic exchange of the region coding for the C terminus of InlA between one epidemic (with an 80-kDa InlA) and one asymptomatic (with a 47-kDa InlA) carriage Listeria monocytogenes strain confirmed the need for this region for internalin entry in vitro. Interestingly, restoration of internalin A functionality did not result in full virulence in chicken embryo assays.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alleles*
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Animals
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Bacterial Proteins / genetics
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Bacterial Proteins / physiology*
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Base Sequence
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Caco-2 Cells
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Chick Embryo
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Humans
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Listeria monocytogenes / pathogenicity*
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Molecular Sequence Data
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Virulence
Substances
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Bacterial Proteins
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internalin protein, Bacteria
Associated data
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GENBANK/AJ784775
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GENBANK/AJ784776
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GENBANK/AJ784777