[Fibrosing pneumopathy induced by cyclothiazide. Apropos of a case]

Rev Mal Respir. 1992;9(2):208-12.
[Article in French]

Abstract

A diffuse interstitial pulmonary fibrosis associated with an idiopathic hepatic cirrhosis occurred in a 79 years old man treated during five years with cyclothiazide and triamterene for a mild systemic hypertension. The outcome was fatal. A provocation test was positive with BAL lymphocytic reaction. Cyclothiazide induced fibrosis is likely.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Antihypertensive Agents / adverse effects*
  • Benzothiadiazines / adverse effects*
  • Bronchoalveolar Lavage Fluid / pathology
  • Diuretics / adverse effects*
  • Drug Combinations
  • Eosinophils / pathology
  • Humans
  • Lymphocytes / pathology
  • Male
  • Pulmonary Fibrosis / chemically induced*
  • Pulmonary Fibrosis / pathology
  • Triamterene / adverse effects*

Substances

  • Antihypertensive Agents
  • Benzothiadiazines
  • Diuretics
  • Drug Combinations
  • cyclothiazide, triamterene drug combination
  • cyclothiazide
  • Triamterene