Background: Tubulo-villous adenomas are common in the colon and rectum, but extremely rare in the vagina. As far as we know, only two cases of tubulo-villous adenoma have ever been reported. We report the third case of enteric-type tubulo-villous adenoma of the vagina.
Case: A 61-year-old woman presented a symptom of intermittent vaginal spotting and a tumor located outside the vaginal introitus near the urethra. The tumor was excised and pathologically confirmed as a tubulo-villous adenoma.
Conclusion: Because some tubulo-villous adenomas in the colon and rectum can progress to the cancer, this case requires long-term follow-up to detect recurrence and malignant transformation.