Haemovigilance in a general university hospital: need for a more comprehensive classification and a codification of transfusion-related events

Vox Sang. 2005 Jan;88(1):22-30. doi: 10.1111/j.1423-0410.2005.00559.x.

Abstract

Background and objectives: The purpose of this study was to analyse the transfusion-related events recorded in a general university hospital.

Materials and methods: The method we used was retrospective analysis of the data collected between 1999 and 2003.

Results: The incidence of transfusion reactions (n = 394) was 4.19 per 1000 blood products distributed: 59% (n = 231) were febrile non-haemolytic transfusion reactions; 22% (n = 88) were caused by allergy; 5% (n = 21) were caused by bacterial infection; and 14% (n = 54) were classified as other reactions. Platelet concentrates gave rise to a significantly greater number of reactions than erythrocyte concentrates and fresh-frozen plasma. Transfusion errors and near-miss events were also observed and were analysed separately. A series of transfusion-related events, such as haemosiderosis, metabolic disturbances or volume overload, were not reported.

Conclusions: Our experience prompts us to propose a more comprehensive classification and codification of transfusion-related events.

MeSH terms

  • Bacterial Infections / etiology
  • Blood Component Transfusion / adverse effects
  • Blood Component Transfusion / statistics & numerical data
  • Classification
  • Data Collection
  • Fever / etiology
  • Forms and Records Control / methods
  • Forms and Records Control / standards*
  • Hospitals, University / standards*
  • Humans
  • Hypersensitivity / etiology
  • Isoantibodies
  • Medical Errors / statistics & numerical data
  • Retrospective Studies
  • Risk Management / methods
  • Risk Management / standards*
  • Transfusion Reaction*

Substances

  • Isoantibodies