Abstract
Inflammatory events during Leishmania braziliensis infection in mice were investigated. Large lesions were directly correlated with the inflammatory reaction but not with parasite burden. Different L. braziliensis strains induce different paces of chemokine expression patterns, leading to diverse cell recruitment and differential inflammatory responses.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Chemokines / biosynthesis
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Chemokines / genetics*
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Gene Expression Profiling
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Kinetics
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Leishmania braziliensis / immunology
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Leishmania braziliensis / metabolism*
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Leishmaniasis, Cutaneous / immunology
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Mice
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RNA, Messenger / metabolism
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Receptors, Chemokine / biosynthesis
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Receptors, Chemokine / genetics
Substances
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Chemokines
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RNA, Messenger
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Receptors, Chemokine