Preprocedural plasma C-reactive protein levels, postprocedural creatine kinase-MB release, and long-term prognosis after successful coronary stenting (four-year results from the GENERATION study)

Michael N Zairis; John A Ambrose; Olga Ampartzidou; Anastassios G Lyras; Stavros J Manousakis; Stamatis S Makrygiannis; Demetrios J Beldekos; Mary C Devoe; Constantine N Fakiolas; Athanasios A Prekates; Christopher D Olympios; Spyros K Argyrakis; Stefanos G Foussas; GENERATION Study Group

doi:10.1016/j.amjcard.2004.09.039

Preprocedural plasma C-reactive protein levels, postprocedural creatine kinase-MB release, and long-term prognosis after successful coronary stenting (four-year results from the GENERATION study)

Am J Cardiol. 2005 Feb 1;95(3):386-90. doi: 10.1016/j.amjcard.2004.09.039.

Authors

Michael N Zairis¹, John A Ambrose, Olga Ampartzidou, Anastassios G Lyras, Stavros J Manousakis, Stamatis S Makrygiannis, Demetrios J Beldekos, Mary C Devoe, Constantine N Fakiolas, Athanasios A Prekates, Christopher D Olympios, Spyros K Argyrakis, Stefanos G Foussas; GENERATION Study Group

Affiliation

¹ Department of Cardiology, Tzanio Hospital, Piraeus, Greece.

PMID: 15670550
DOI: 10.1016/j.amjcard.2004.09.039

Abstract

Increased creatine kinase-MB isoenzymes after coronary stenting are common, and many studies have suggested an association of this increase with an adverse long-term prognosis. How such postprocedural creatine kinase-MB release affects long-term prognosis remains unclear. Whether any actual causal relation exists remains unanswered.

MeSH terms

Aged
C-Reactive Protein / metabolism*
Chi-Square Distribution
Coronary Disease / blood*
Coronary Disease / therapy*
Creatine Kinase / metabolism*
Creatine Kinase, MB Form
Female
Humans
Isoenzymes / metabolism*
Male
Middle Aged
Predictive Value of Tests
Prognosis
Prospective Studies
Regression Analysis
Statistics, Nonparametric
Stents*

Substances

Isoenzymes
C-Reactive Protein
Creatine Kinase
Creatine Kinase, MB Form