Dose-effect relationship for radiotherapy after incomplete resection of atypical neurocytomas

Radiother Oncol. 2005 Jan;74(1):67-9. doi: 10.1016/j.radonc.2004.08.008.

Abstract

Neurocytomas with atypical histology or high proliferation activity are named atypical. All reported cases were reviewed. After incomplete resection, radiotherapy improved local-control (P<0.001) and survival (P=0.02). Doses (EQD2) >54 Gy were associated with better 5-year local control (84% versus 55%, P=0.05) and 5-year-survival (84% versus 65%, P=0.18) than doses < or =54 Gy.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Brain Neoplasms / radiotherapy*
  • Cell Proliferation
  • Child
  • Child, Preschool
  • Disease Progression
  • Dose-Response Relationship, Radiation
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neurocytoma / radiotherapy*
  • Retrospective Studies
  • Survival Analysis
  • Treatment Outcome