Abstract
Patients with acute myocardial infarction were randomly assigned to receive direct percutaneous coronary intervention (PCI) or pretreatment with intravenous monteplase followed by PCI. Although the combination of monteplase and PCI did not alter mortality compared with direct PCI, there was a dramatic reduction in the cardiac event rate over a 2-year follow-up compared with direct PCI.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Angioplasty, Balloon, Coronary*
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Coronary Angiography
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Emergency Treatment
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Female
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Follow-Up Studies
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Humans
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Injections, Intravenous
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Male
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Middle Aged
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Myocardial Infarction / therapy*
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Plasminogen Activators / therapeutic use*
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Prospective Studies
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Secondary Prevention
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Thrombolytic Therapy*
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Treatment Outcome
Substances
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monteplase
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Plasminogen Activators