Abstract
An n-pentenyl furanosyl-1,2-orthoester can function as a donor or be rearranged leading to an n-pentenyl furanoside acceptor which is glycosylated by its progenitor, regioselectively or doubly, thereby enabling rapid fabrication of a multibranched dodecasaccharide, known to possess a wide variety of biological interactions.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Antineoplastic Agents / chemical synthesis*
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Antineoplastic Agents / chemistry
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Antitubercular Agents / chemical synthesis*
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Antitubercular Agents / chemistry
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Bridged Bicyclo Compounds, Heterocyclic / chemistry
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Carbohydrate Conformation
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Furans / chemical synthesis*
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Furans / chemistry
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Molecular Sequence Data
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Mycobacterium / chemistry*
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Mycobacterium / classification
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Pentoses / chemistry
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Polysaccharides / chemical synthesis*
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Polysaccharides / chemistry
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Species Specificity
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Stereoisomerism
Substances
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Antineoplastic Agents
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Antitubercular Agents
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Bridged Bicyclo Compounds, Heterocyclic
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Furans
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Pentoses
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Polysaccharides