Mutations in the human BOULE gene are not a major cause of impaired spermatogenesis

G Henrike Westerveld; Sjoerd Repping; Nico J Leschot; Fulco van der Veen; M Paola Lombardi

doi:10.1016/j.fertnstert.2004.10.013

Mutations in the human BOULE gene are not a major cause of impaired spermatogenesis

Fertil Steril. 2005 Feb;83(2):513-5. doi: 10.1016/j.fertnstert.2004.10.013.

Authors

G Henrike Westerveld¹, Sjoerd Repping, Nico J Leschot, Fulco van der Veen, M Paola Lombardi

Affiliation

¹ Center for Reproductive Medicine, Department of Obstetrics and Gynaecology, Academic Medical Center, Meibergdreef 9, H4-205, 1105 AZ Amsterdam, The Netherlands. [email protected]

PMID: 15705409
DOI: 10.1016/j.fertnstert.2004.10.013

Abstract

Mutation screening of the BOULE gene in 156 men with azoospermia or severe oligozoospermia revealed no relevant mutations; thus, mutations in BOULE can be eliminated as a major cause of impaired spermatogenesis.

MeSH terms

Genetic Testing
Humans
Infertility, Male / genetics*
Male
Mutation, Missense
Oligospermia / genetics
RNA-Binding Proteins / genetics*
Spermatogenesis / genetics*

Substances

BOLL protein, human
RNA-Binding Proteins